Table of Contents

Cell Structure & Function

Nucleus

Cell Wall....

Cytoplasm/Cytoskeleton

Organelles

Plasma Membrane

Developmental Themes

Cool Cell Biology Links

Viruses

Main Page






































































Nucleus Banner

General Links

The Cell Nucleus - An extremely nice page. Discusses the general functions of the cell nucleus and numerous other structures of the nucleus, including: the nuclear envelope, nuclear lamina, nuclear pore complex, active transport, signaling, and more. Also provides very nice images of the cell nucleus and its structures.  Additional links available.

The Nucleus Ultrastructure - Begins with an outline of the discussion, scroll down to find the actual discussion.  A very detailed page about the nucleus and the structures that it is made up of.

Back to Top

Chromosomes

Composed of chromatin, which is two strands of helical DNA and its associated proteins, called histones. During cell division, the DNA becomes tightly wound around the histones to form structures called nucleosomes, which are further coiled and packaged into the highly condensed chromosome.

The Genetic Location Database - Ldb is a database for constructing fully integrated genetic and physical maps.

The Dog Genome Project - A study being performed by several institutions in which they are attempting to map out the chromosomal genome of dogs.

Triplo-X-Syndrome Database - Discusses how to gather information on the Triplo-X-Syndrome.

Back to Top

Mitosis

In mitosis, the cell makes a duplicate copy of itself that contains the same number of chromosomes as contained in the original. The somatic (nonreproductive) cells of higher organisms divide by mitosis.

An Introduction to Mitosis - A discussion on mitosis which is followed by discussions on each individual step in the mitosis process (i.e. prophase, metaphase…). Includes links to actual photographs of each step (the images take a long time to down view, but are very nice).

Mitosis and Meiosis - Provides a discussion on each individual step in the mitosis process. This is followed by a discussion on meiosis, which includes information on synapsis and crosssing over.

The Cell Cycle & Mitosis Tutorial - An introduction to the cell cycle and to mitosis.

An Introduction to Mitosis - A fairly detailed discussion on the process of mitosis.

Back to Top

Meiosis

In meiosis, the cell divides twice, ultimately yielding four daughter cells. The first division separates the homologous chromosomes so that the resulting cells contain only half the number of chromosomes found in the original cell. The second division separates sister chromatids (as in mitosis), resulting in a total of four haploid cells.

Meiosis - Provides a short description of meiosis I and meiosis II, including short discussions on each stage.  Also provides information on recombination, crossing over, random assortment of homologues, and fertilization.

Animated Meiosis      Movie

- Small, short animations on meiosis, mitosis, and a few other processes.

The Hawley Lab: Meiosis - Discusses meiosis and the way in which it operates. Also provides some examples of organisms whose meiosis mechanisms vary from the norm.

Cell Reproduction - Includes short discussions on the meiotic cycle and animal, plant, and fungal reproduction.

Meiosis and Cytokinesis - An image of meiosis which is accompanied by a small introduction of what is being viewed.

Meiosis Tutorial - Provides valuable information for better understanding the meiosis process.
Meiosis Movie (927K) Movie

Back to Top

Transcription

Enzymes (RNA polymerases) interact with or "read" a sequence of DNA to make an RNA version of the DNA (gene), often called an mRNA or transcript.

Basal Transcription Factor Information - A very advanced research page. Provides a brief introduction to basal transcription factors, followed by a database of basal transcription factors.

Transcription - Provides a brief overview of transcription.

Back to Top

Splicing

In eukaryotic cells, after DNA is transcribed, the resulting RNA must often be processed further by enzymes that remove or "splice" specific regions of the sequence. By altering the splicing of each transcript, many different polypeptides can result from one original DNA sequence.

Home Gene-Splicing Kit - An advertisement for a fun little program which allows you to imitate gene splicing.  Provides a sample game.

Gene Splicing Commemorative Stamp - A funny little image of a stamp developed in honor of gene splicing.

How to Splice a Gene - Provides the procedure first used in performing gene splicing.

Back to Top

Nucleolus

This is the region within the nucleus where rRNA is transcribed and combined with proteins to make ribosomes. In this region, chromosomal DNA forms loops, exposing the rRNA genes to be transcribed.

The Nucleolus  - A brief overview of the nucleolus.  Provides a nice labeled image.

Back to Top

Some Labs Sites

Paul Schedl - The general goal of our research on Drosophila melanogaster is to gain insights into some of the mechanisms governing the utilization of genetic information in eukaryotes.

Meiosis Laboratory - Institute of Cytology and Genetics, Russia.

Nuclear Architecture and Chromosome Organization - Laboratory of John W. Sedat -research is aimed at understanding the organization of chromosomes within the nucleus, the detailed architecture of the chromosomes themselves, and the functional roles this organization plays in determining chromosome behavior.

Back to Top